Carbamazepine impurity

CAS: 3564-73-6

Ref. 3D-FC139258

Product Information

• Name: Carbamazepine impurity
• Synonyms: 10,11-Dihydrocarbamazepine, 10,11-Dihydro-5H-dibenz[b,f]azepine-5-carboxamide, 10,11-dihydro-5H-dibenzo[b,f]azepine-5-carboxamide, 5H-Dibenz[b,f]azepine-5-carboxamide, 10,11-dihydro-, Gp 26-301

Description

Carbamazepine is a drug that has been used to treat epileptic seizures and trigeminal neuralgia. Impurities in the drug are removed by using chromatographic methods, such as high-performance liquid chromatography (HPLC). The rotarod test is an animal model of motor coordination and balance that can be used to assess the effects of drugs on these functions. Carbamazepine impurities may cause depression and have an epileptic effect on animals. Chronic exposure to carbamazepine can lead to drug reactions and gene polymorphisms, which may alter the metabolism of the drug. Analytical methods for determining carbamazepine impurities include HPLC, gas chromatography mass spectrometry (GC-MS), and thin-layer chromatography (TLC).

• Brand: Biosynth

Chemical properties

• Molecular weight: 238.28 g/mol
• Formula: C₁₅H₁₄N₂O
• Purity: Min. 95%
• InChI: InChI=1S/C15H14N2O/c16-15(18)17-13-7-3-1-5-11(13)9-10-12-6-2-4-8-14(12)17/h1-8H,9-10H2,(H2,16,18)
• InChI key: InChIKey=PHNLCHMJDSSPDQ-UHFFFAOYSA-N
• SMILES: NC(=O)N1c2ccccc2CCc2ccccc21