Cholesterol chloroformate

CAS: 7144-08-3

Ref. 3D-FC14186

Product Information

• Name: Cholesterol chloroformate
• Synonyms: Cholest-5-en-3-ol (3b)-, 3-chloroformate
• Brand: Biosynth
• Description: Cholesterol chloroformate is a cholesterol derivative that has been shown to have good solubility in water. It is a white crystalline solid that is insoluble in ether, benzene, and chlorinated hydrocarbons. The compound has been used as a phase-transition temperature indicator and has been shown to be more resistant to degradation by enzymes than steric interactions. Cholesterol chloroformate is also an intermediate for the synthesis of other compounds such as cholesteryl sulfate and dextran sulfate. This compound binds to the Toll-like receptor 4 (TLR4) on cells, triggering an inflammatory response and activating the immune system. Cholesterol chloroformate can be used to study tumor cell growth by inhibiting mitosis in mouse tumors with subcutaneous injections of this agent.

Chemical properties

• Molecular weight: 449.11 g/mol
• Formula: C₂₈H₄₅ClO₂
• Purity: Min. 95%