Cevimeline hydrochloride hemihydrate

CAS: 153504-70-2

Ref. 3D-FC150175

Product Information

• Name: Cevimeline hydrochloride hemihydrate
• Synonyms: CevimelineHCl, C07772, Spiro[1-azabicyclo[2.2.2]octane-3,5'-[1,3]oxathiolane], 2'-methyl-, hydrochloride, hydrate (2:1), cis-, Spiro[1-azabicyclo[2.2.2]octane-3,5'-[1,3]oxathiolane], 2'-methyl-, hydrochloride, hydrate (2:2:1), (2'R,3R)-rel-, (2R,2'R)-2'-methylspiro[4-azabicyclo[2.2.2]octane-2,5'-[1,3]oxathiolane] hydrochloride hydrate (2:2:1), (2R,2'R)-2'-methylspiro[4-azabicyclo[2.2.2]octane-2,5'-[1,3]oxathiolane] hydrochloride (1:1)

Description

Cevimeline hydrochloride hemihydrate is a cholinergic agent that is used to treat dry mouth. It activates muscarinic receptors in the salivary gland, leading to increased salivation. Cevimeline hydrochloride hemihydrate has been shown to be well tolerated in clinical trials and does not have significant side-effects. There is some evidence for its efficacy in reducing disease activity in geriatric patients with Sjögren's syndrome, although this has not been demonstrated statistically.

• Brand: Biosynth

Chemical properties

• Molecular weight: 489.56 g/mol
• Formula: C₂₀H₃₈Cl₂N₂O₃S₂
• Purity: Min. 95%
• Color/Form: Powder