9-Chloroacridine

Ref. 3D-FC151363

Product Information

• Name: 9-Chloroacridine
• Brand: Biosynth
• Description: 9-Chloroacridine is an acridone that has potent anti-inflammatory activity. It binds to the endothelin-A receptor, which is a G protein-coupled receptor. 9-Chloroacridine also inhibits neutrophil migration and the production of reactive oxygen species. It was shown to have significant cytotoxicity in cell culture and to react with hydrochloric acid to form two chemical species: amines and protonated molecules. Molecular docking analysis has been used to show that 9-chloroacridine interacts with the enzyme dihydropteridine reductase, which is involved in pteridine synthesis. The molecule was also shown to inhibit the growth of human cancer cells in vitro. This drug may be useful as a chemotherapy agent for treatment of cancer.

Chemical properties

• Molecular weight: 213.66 g/mol
• Formula: C₁₃H₈ClN
• Purity: Min. 95%
• InChI: InChI=1S/C13H8ClN/c14-13-9-5-1-3-7-11(9)15-12-8-4-2-6-10(12)13/h1-8H
• InChI key: InChIKey=BPXINCHFOLVVSG-UHFFFAOYSA-N
• SMILES: Clc1c2ccccc2nc2ccccc12