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Selonsertib
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Selonsertib

CAS: 1448428-04-3

Ref. 3D-FC157241

25mg
338.00 €
50mg
457.00 €
100mg
542.00 €
Estimated delivery in United States, on Tuesday 18 Feb 2025

Product Information

Name:
Selonsertib
Synonyms:
  • 5-(4Cyclopropyl- 1H- imidazol- 1- yl) - 2- fluoro- N- (6- (4- isopropyl- 4H- 1
  • 2
  • 4- triazol- 3- yl) pyridin- 2- yl) - 4- methylben zamide
Description:

Selonsertib is a highly selective inhibitor of the ATP-binding cassette transporter (ABCA1) that belongs to the class of glp-1 analogues. It is used in combination with other drugs for the treatment of bowel disease, autoimmune diseases, and skin cancer. Selonsertib has been shown to be active against a number of cell types and is also effective in models of metabolic disorders such as hepatic steatosis and kidney fibrosis. Selonsertib blocks ABCA1 by binding to its ATP-binding site, inhibiting cholesterol efflux from cells. This drug may work by restoring mitochondrial membrane potential, which may help prevent or reverse cellular damage caused by oxidative stress.

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
445.49 g/mol
Formula:
C24H24FN7O
Purity:
Min. 95%
InChI:
InChI=1S/C24H24FN7O/c1-14(2)32-13-27-30-23(32)19-5-4-6-22(28-19)29-24(33)17-10-21(15(3)9-18(17)25)31-11-20(26-12-31)16-7-8-16/h4-6,9-14,16H,7-8H2,1-3H3,(H,28,29,33)
InChI key:
InChIKey=YIDDLAAKOYYGJG-UHFFFAOYSA-N
SMILES:
Cc1cc(F)c(C(=O)Nc2cccc(-c3nncn3C(C)C)n2)cc1-n1cnc(C2CC2)c1
MDL:
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HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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