Gimeracil

CAS: 103766-25-2

Ref. 3D-FC15749

Product Information

• Name: Gimeracil
• Synonyms: 5-Chloro-4-hydroxy pyridine-2(1H)-one, 2(1H)-Pyridinone, 5-chloro-4-hydroxy-, 5-Chloro-2,4-dihydroxypyridine, 5-Chloro-4-hydroxy-2(1H)-pyridinone, 5-Chloro-4-hydroxy-2-pyridone, 5-Chloropyridine-2,4-Diol, Cdhp, Gimestat

Description

Gimeracin is a prodrug that is hydrolyzed in vivo to gimeracil and acetic acid. Gimeracin has been shown to inhibit glucose uptake into cells, which may be due to its inhibition of the sodium-glucose co-transporter 1 (SGLT1). Gimeracin has also been shown to produce cytotoxic effects on human cancer cells, with the potential for radiation therapy. The mechanism of toxicity may be related to the production of reactive oxygen species.

The 6-Fluoro-3-indoxyl-beta-D-galactopyranoside is an antituberculosis drug that belongs to the class of rifamycins. It is the most active of the rifamycins for the treatment of tuberculosis. Rifapentine inhibits bacterial growth by binding to DNA-dependent RNA polymerase, thereby preventing transcription and replication. The high frequency of human activity has been shown using

• Brand: Biosynth

Chemical properties

• Molecular weight: 145.54 g/mol
• Formula: C₅H₄NO₂Cl
• Purity: Min. 98 Area-%
• Color/Form: Slightly Yellow Powder
• InChI: InChI=1S/C5H4ClNO2/c6-3-2-7-5(9)1-4(3)8/h1-2H,(H2,7,8,9)
• InChI key: InChIKey=ZPLQIPFOCGIIHV-UHFFFAOYSA-N
• SMILES: O=c1cc(O)c(Cl)c[nH]1