Product Information
Name:Crisaborole
Synonyms:
- AN27284-[(1,3-Dihydro-1-hydroxy-2,1-benzoxaborol-5-yl)oxy]benzonitrile
Brand:Biosynth
Description:Crisaborole is a topical antimicrobial peptide that was approved by the FDA in 2017 for the treatment of mild to moderate atopic dermatitis and eczema. It belongs to a class of drugs called small-molecule inhibitors of phosphodiesterase 4 (PDE4). PDE4 is an enzyme that hydrolyzes cyclic adenosine monophosphate (cAMP) and thereby reduces the levels of cAMP in cells. Crisaborole binds to the PDE4 enzyme and blocks its activity, leading to an increase in the level of cAMP. This increased concentration of cAMP leads to suppression of inflammation, which is a major symptom associated with skin diseases such as dermatitis and eczema.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:251.05 g/mol
Formula:C14H10BNO3
Purity:Min. 95%
Color/Form:Powder
InChI:InChI=1S/H3N/h1H3
InChI key:InChIKey=QGZKDVFQNNGYKY-UHFFFAOYSA-N
SMILES:N#Cc1ccc(Oc2ccc3c(c2)COB3O)cc1
Technical inquiry about: Crisaborole
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