Colestipol
CAS:
Ref. 3D-FC184561
Product Information
Name:Colestipol
Brand:Biosynth
Description:Colestipol is a bile acid sequestrant, which is a type of polymeric anion-exchange resin derived from a synthetic, non-absorbable source. Its mode of action involves binding bile acids in the intestine, thereby interrupting their enterohepatic circulation. This binding process forms an insoluble complex that is excreted in feces, reducing the bile acid pool and prompting the liver to use circulating cholesterol to synthesize new bile acids. Consequently, this results in a decrease in serum cholesterol levels.Colestipol is primarily used in the management of hypercholesterolemia, particularly in patients who cannot tolerate statins or require additional cholesterol-lowering support. Its applications extend to both primary and secondary prevention of coronary artery disease due to its role in lowering low-density lipoprotein (LDL) cholesterol levels. While effective, its usage must be carefully monitored due to potential gastrointestinal side effects and possible interactions with the absorption of other medications and nutrients.
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