cis-Capsaicin

CAS: 25775-90-0

Ref. 3D-FC19671

Product Information

• Name: cis-Capsaicin
• Synonyms: (6Z)-N-[(4-Hydroxy-3-methoxyphenyl)methyl]-8-methyl-6-nonenamide(Z)-8-Methyl-N-vanillyl-6-nonenamide, (6E)-N-(4-hydroxy-3-methoxybenzyl)-8-methylnon-6-enamide, (6Z)-N-(4-hydroxy-3-methoxybenzyl)-8-methylnon-6-enamide, (6Z)-N-[(4-Hydroxy-3-methoxyphenyl)methyl]-8-methyl-6-nonenamide, (Z)-8-Methyl-N-vanillyl-6-nonenamide, (Z)-N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methyl-6-nonenamide, 6-Nonenamide, 8-methyl-N-vanillyl-, (Z)-, 6-Nonenamide, N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methyl-, (6Z)-, 6-Nonenamide, N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methyl-, (Z)-, Capsaicin, cis-, Civamide, Zucapsaicin
• CAS: 25775-90-0

Description

Cis-Capsaicin is a non-pungent capsaicin analogue with high affinity for the TRPV1 receptor. It has been shown to be a potent inhibitor of the JAK1 kinase, which is involved in the development of diabetic neuropathy. Cis-Capsaicin also has anti-inflammatory and analgesic effects, and can be used as a treatment for eye disorders such as dry eye syndrome. The therapeutic efficacy of cis-Capsaicin has been shown in clinical trials for the treatment of infectious diseases, such as HIV and tuberculosis, and autoimmune diseases, such as rheumatoid arthritis. In addition, cis-capsaicin has been shown to have cardiac effects in rats by reducing myocardial oxygen consumption.

• Brand: Biosynth

Chemical properties

• Molecular weight: 305.41 g/mol
• Formula: C₁₈H₂₇NO₃
• Purity: Min. 95%
• Color/Form: White Powder
• InChI: InChI=1S/C18H27NO3/c1-14(2)8-6-4-5-7-9-18(21)19-13-15-10-11-16(20)17(12-15)22-3/h6,8,10-12,14,20H,4-5,7,9,13H2,1-3H3,(H,19,21)/b8-6-
• InChI key: InChIKey=YKPUWZUDDOIDPM-VURMDHGXSA-N
• SMILES: COc1cc(CNC(=O)CCCC/C=C\C(C)C)ccc1O