5-Carboxyfluorescein diacetate

CAS: 79955-27-4

Ref. 3D-FC19776

Product Information

• Name: 5-Carboxyfluorescein diacetate
• Synonyms: 5-FAM DA, 5-CFDA, 5-Carboxy-di-O-acetylfluorescein
• Brand: Biosynth
• Description: 5-Carboxyfluorescein diacetate is a reactive dye that can be used as a model system to study the effects of reactive species on biological molecules. It has been shown to inhibit mitochondrial membrane potential and activate detoxification enzymes in rats. 5-Carboxyfluorescein diacetate also induces apoptosis in human leukemia cells and inhibits the proliferation of human breast cancer cells. The effect of 5-carboxyfluorescein diacetate on collagen synthesis in a rat wound healing model has been investigated, with an increase in collagen found after treatment. This drug can also cause immunomodulatory effects by inhibiting macrophage activity and increasing T lymphocytes.

Chemical properties

• Molecular weight: 460.39 g/mol
• Formula: C₂₅H₁₆O₉
• Purity: Min. 95 Area-%
• Color/Form: White Powder
• InChI: InChI=1S/C25H16O9/c1-12(26)31-15-4-7-19-21(10-15)33-22-11-16(32-13(2)27)5-8-20(22)25(19)18-6-3-14(23(28)29)9-17(18)24(30)34-25/h3-11H,1-2H3,(H,28,29)
• InChI key: InChIKey=WPUZGNPQMIWOHE-UHFFFAOYSA-N
• SMILES: CC(=O)Oc1ccc2c(c1)Oc1cc(OC(C)=O)ccc1C21OC(=O)c2cc(C(=O)O)ccc21