Carboxymefloquine
CAS: 35853-50-0
Ref. 3D-FC19787
5mg | 341.00 € | ||
10mg | 449.00 € | ||
25mg | 724.00 € | ||
50mg | 905.00 € | ||
100mg | 1,023.00 € |
Product Information
- 2,8-Bis(trifluoromethyl)-4-quinolinecarboxylic acidRo 21-5104
- 4-Quinolinecarboxylic Acid, 2,8-Bis(Trifluoromethyl)-
Carboxymefloquine is a cytochrome P450 inhibitor that is used as an antiparasitic drug in the treatment of intestinal amebiasis and malaria. Carboxymefloquine inhibits the activity of various cytochrome P450 enzymes, which are involved in the metabolism of other drugs. Carboxymefloquine has been shown to decrease the elimination rate of quinidine and propranolol, which may lead to increased concentrations of these drugs in plasma. Carboxymefloquine also has a long terminal half-life and may cause drug interactions with other drugs that are metabolized by cytochrome P450 enzymes. Clinical studies have shown that carboxymefloquine can be used for the treatment of inflammatory bowel disease (IBD). The clinical relevance of this drug is not fully understood because it does not inhibit prostaglandin synthesis or induce apoptosis in intestinal epithelial cells, unlike other IBD treatments such as
Chemical properties
Technical inquiry about: 3D-FC19787 Carboxymefloquine
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