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Carboxymefloquine
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Carboxymefloquine

CAS: 35853-50-0

Ref. 3D-FC19787

5mg
341.00 €
10mg
449.00 €
25mg
724.00 €
50mg
905.00 €
100mg
1,023.00 €
Estimated delivery in United States, on Tuesday 10 Dec 2024

Product Information

Name:
Carboxymefloquine
Synonyms:
  • 2,8-Bis(trifluoromethyl)-4-quinolinecarboxylic acidRo 21-5104
  • 4-Quinolinecarboxylic Acid, 2,8-Bis(Trifluoromethyl)-
Description:

Carboxymefloquine is a cytochrome P450 inhibitor that is used as an antiparasitic drug in the treatment of intestinal amebiasis and malaria. Carboxymefloquine inhibits the activity of various cytochrome P450 enzymes, which are involved in the metabolism of other drugs. Carboxymefloquine has been shown to decrease the elimination rate of quinidine and propranolol, which may lead to increased concentrations of these drugs in plasma. Carboxymefloquine also has a long terminal half-life and may cause drug interactions with other drugs that are metabolized by cytochrome P450 enzymes. Clinical studies have shown that carboxymefloquine can be used for the treatment of inflammatory bowel disease (IBD). The clinical relevance of this drug is not fully understood because it does not inhibit prostaglandin synthesis or induce apoptosis in intestinal epithelial cells, unlike other IBD treatments such as

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
309.17 g/mol
Formula:
C12H5F6NO2
Purity:
Min. 95 Area-%
Color/Form:
Orange Powder
InChI:
InChI=1S/C12H5F6NO2/c13-11(14,15)7-3-1-2-5-6(10(20)21)4-8(12(16,17)18)19-9(5)7/h1-4H,(H,20,21)
InChI key:
InChIKey=QJTJIQBSZLFWFS-UHFFFAOYSA-N
SMILES:
O=C(O)c1cc(C(F)(F)F)nc2c(C(F)(F)F)cccc12
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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