6-Chloro L-tryptophan

CAS: 33468-35-8

Ref. 3D-FC19949

Product Information

• Name: 6-Chloro L-tryptophan
• Synonyms: 6-Chloro (S)-tryptophan6-ChlorotryptophanL-6-Chlorotryptophan, (2S)-2-Amino-3-(6-chloro-1H-indol-3-yl)propanoic acid, (S)-2-Amino-3-(6-chloro-1H-indol-3-yl)propanoic acid, 6-Chloro-<span class="text-smallcaps">L</span>-tryptophan, 6-Chloro-L-tryptophan, 6-Chloro-L-tryptophane, 6-Chlorotryptophan, <span class="text-smallcaps">L</span>-6-Chlorotryptophan, <span class="text-smallcaps">L</span>-Tryptophan, 6-chloro-, H-6-Cl-Trp-OH, L-6-Chlorotryptophan, Tryptophan, 6-chloro-, <span class="text-smallcaps">L</span>-, Tryptophan,6-chloro-, L-

Description

6-Chloro L-tryptophan is an aminotransferase inhibitor that is activated by the enzyme, aminotransferase. 6-Chloro L-tryptophan has been shown to inhibit the growth of tumour cells, which may be due to its ability to induce apoptosis and inhibit the production of tumour necrosis factor alpha (TNFα). This drug has also been shown to exhibit antiinflammatory effects and can inhibit the activation of microglia in human brain cells. 6-Chloro L-tryptophan is activated by liver cells and human macrophages, leading to the inhibition of 3-hydroxyanthranilic acid synthesis and the neutralization of acidic conditions. It also inhibits uptake in thp-1 cells, a type of white blood cell that lines blood vessels in lymph nodes. In addition, 6-chloro L-tryptophan has been shown to have antiviral effects

• Brand: Biosynth

Chemical properties

• Molecular weight: 238.67 g/mol
• Formula: C₁₁H₁₁ClN₂O₂
• Purity: Min. 98 Area-%
• Color/Form: Powder
• InChI: InChI=1S/C11H11ClN2O2/c12-7-1-2-8-6(3-9(13)11(15)16)5-14-10(8)4-7/h1-2,4-5,9,14H,3,13H2,(H,15,16)/t9-/m0/s1
• InChI key: InChIKey=FICLVQOYKYBXFN-VIFPVBQESA-N
• SMILES: N[C@@H](Cc1c[nH]c2cc(Cl)ccc12)C(=O)O