2-Chloro-3',4'-dihydroxyacetophenone

CAS: 99-40-1

Ref. 3D-FC19955

Product Information

• Name: 2-Chloro-3',4'-dihydroxyacetophenone
• Synonyms: 4-(Chloroacetyl)catechol, 1-Chloroacetyl-3,4-dihydroxybenzene, 2-Chloro-1-(3,4-Dihydroxyphenyl)Ethanone, 2-Chloro-1-(3,4-dihydroxyphenyl)-1-ethanone, 2-Chloro-3,4-Dihydroxyacetophenone, 3,4-Dihydroxy-α-chloroacetophenone, 3,4-Dihydroxyphenacyl chloride, Acetophenone, 2-chloro-3′,4′-dihydroxy-, Acetophenone, α-chloro-3,4-dihydroxy-, Chloracetyl catechol, Ethanone, 2-chloro-1-(3,4-dihydroxyphenyl)-, NSC 13905, NSC 17869, alpha-Chloro-3,4-dihydroxyacetophenone, α-Chloro-3′,4′-dihydroxyacetophenone

Description

2-Chloro-3',4'-dihydroxyacetophenone is a potent inhibitor of two enzymes that are involved in the synthesis of fatty acids: 3-ketoacyl-coenzyme A synthase and 3-hydroxyacyl-coenzyme A dehydrogenase. This inhibition leads to the accumulation of acetate and reduced levels of fatty acids, which are important for cell growth. 2-Chloro-3',4'-dihydroxyacetophenone has been shown to be effective against Pseudomonas aeruginosa, Staphylococcus aureus, and Serratia epidermidis. 2-Chloro-3',4'-dihydroxyacetophenone inhibits the production of reactive oxygen species (ROS) by inhibiting lipid peroxidation in human liver cells and it has also been shown to have antiradical activity.

• Brand: Biosynth

Chemical properties

• Molecular weight: 186.59 g/mol
• Formula: C₈H₇ClO₃
• Purity: Min. 98.0 Area-%
• Color/Form: Off-White To Brown Solid
• InChI: InChI=1S/C8H7ClO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,10-11H,4H2
• InChI key: InChIKey=LWTJEJCZJFZKEL-UHFFFAOYSA-N
• SMILES: O=C(CCl)c1ccc(O)c(O)c1