4-Chloro-6-methoxyindole

CAS: 93490-31-4

Ref. 3D-FC20152

Product Information

• Name: 4-Chloro-6-methoxyindole
• Synonyms: 1H-Indole, 4-chloro-6-methoxy-, 4-chloro-6-methoxy-1H-indole

Description

4-Chloro-6-methoxyindole is a potent inducer of the cytochrome P450 system, which is involved in the metabolism of xenobiotics. It has been shown to induce glucosinolates and casein in mammalian cells. 4-Chloro-6-methoxyindole also induces the formation of reactive oxygen species (ROS) and DNA damage. Several genotoxic effects have been observed, including genotoxic activities that are associated with carcinogenic potential. 4-Chloro-6-methoxyindole has been shown to induce hamster v79 cells at low doses and human v79 cells at high doses, suggesting that it may be carcinogenic in humans.

• Brand: Biosynth

Chemical properties

• Molecular weight: 181.62 g/mol
• Formula: C₉H₈ClNO
• Purity: Min. 95%
• InChI: InChI=1S/C9H8ClNO/c1-12-6-4-8(10)7-2-3-11-9(7)5-6/h2-5,11H,1H3
• InChI key: InChIKey=ROZQWTXWGPFHST-UHFFFAOYSA-N
• SMILES: COc1cc(Cl)c2cc[nH]c2c1