Product Information
- 4-Chloro-b-oxo-benzenepropanenitrile3-(4-Chlorophenyl)-3-oxopropanenitrile3-Oxo-3-(4-chlorophenyl)propionitrile
- 3-(4-Chlorophenyl)-3-oxopropanenitrile
- 3-(4-Chloro-phenyl)-3-oxo-propionitrile
- 3-(4-Chlorphenyl)-3-oxopropanonitril
- Benzenepropanenitrile, 4-chloro-beta-oxo-
- 4-Chlorophenyl cyanomethyl ketone
4-Chlorobenzoylacetonitrile is an efficient method for the synthesis of aldehydes from formyl compounds. It has been used to synthesize a variety of organic compounds, including drugs, pharmaceuticals, and natural products. This reaction takes place in three steps: (1) addition of thiourea to the formyl compound; (2) conversion of the thiourea to a thiol derivative; and (3) treatment with molybdenum trioxide. The second step is stereoselective, so it can be used to produce either R or S-enantiomers. The final product is an aldehyde with a formyl group at the alpha position. In this reaction mechanism, hydrogen bonds are broken by cleaving a C-H bond adjacent to an active methylene group. The reaction is initiated by irradiation or heating due to the release of energy that is stored in these bonds.
Chemical properties
Technical inquiry about: 3D-FC20199 4-Chlorobenzoylacetonitrile
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