2-Chlorophenothiazine

CAS: 92-39-7

Ref. 3D-FC20303

Product Information

• Name: 2-Chlorophenothiazine
• Synonyms: 2-Chloro-10H-phenothiazineNSC 170953NSC 17469, 2-Chloro-10H-phenothiazine, Phenothiazine, 2-chloro-, 10H-Phenothiazine, 2-chloro-, NSC 170953

Description

2-Chlorophenothiazine is a chemical substance that can be used as a pharmacological agent. It is classified as an amp-activated protein, which means it binds to the active site of the enzyme phospholipase A2 (PLA2) and thus inhibits its function. 2-Chlorophenothiazine has been shown to inhibit fatty acid biosynthesis by binding to the catalytic site of the enzyme acetyl coenzyme A carboxylase (ACC). This compound also has been shown to have mutagenic properties in bacterial systems, as well as being able to cause damage to red blood cells by inhibiting electron transport in mitochondria. 2-Chlorophenothiazine is also used for treating cancerous cells, such as squamous carcinoma. The activation energy required for 2-chlorophenothiazine's reaction with squamous carcinoma cells is lower than that required for other carcinomas such as leukemia or colon cancer cells.
2-

• Brand: Biosynth

Chemical properties

• Molecular weight: 233.72 g/mol
• Formula: C₁₂H₈ClNS
• Purity: Min. 95%
• Color/Form: Off-White Powder
• InChI: InChI=1S/C12H8ClNS/c13-8-5-6-12-10(7-8)14-9-3-1-2-4-11(9)15-12/h1-7,14H
• InChI key: InChIKey=KFZGLJSYQXZIGP-UHFFFAOYSA-N
• SMILES: Clc1ccc2c(c1)Nc1ccccc1S2