Cisplatin

CAS: 15663-27-1

Ref. 3D-FC20460

Product Information

• Name: Cisplatin
• Synonyms: cis-Platinum(II) diammine dichloridecis-Dichlorodiammine platinum(II), (SP-4-2)-Diamminedichloroplatinum, Abiplatin, Biocisplatinum, Briplatin, CP Ethypharm, Cacp, Cddp, Cis-Platinum(Ii)Diammine Dichloride, Cismaplat, Cisplatine, Cisplatine Mylan, Cisplatino, Cisplatinum, Cisplatyl, Citoplatino, Citoplax, Cpdc, Cpdd, Cppd, DDP, DDP (antitumor agent), DichlorodiammineplatinumIIyelloworangextl, Fauldiscipla, IA-call, Kemoplat, Lederplatin, LiPlaCis, Lipoplatin, Maruko, Neoplatin, Nsc 119875, Platamine, Platiblastin, Platidiam, Platinex, Platinol, Platinol AQ, Platinoxan, Platinum, diamminedichloro-, (SP-4-2)-, Platinum, diamminedichloro-, cis-, Platinumdiamminechloride, Platistin, Platosin, Rand, Randa, SPI 077 (complex), Spi 077, Spi 077B103, Tr 170, cis-DDP, cis-Diaminedichloridoplatinum(II), cis-Diaminedichloroplatinum, cis-Diaminedichloroplatinum(II), cis-Diaminodichloroplatinum(II), cis-Diamminedichloroplatinum, cis-Diamminedichloroplatinum(II), cis-Diammineplatinum(II), cis-Diammineplatinum(II) dichloride, cis-Dichlorodiammineplatinum, cis-Dichlorodiammineplatinum(II), cis-Platin, cis-Platine, cis-Platinous diaminodichloride, cis-Platinum, cis-Platinum II, cis-Platinum diaminodichloride, cis-Platinum(II) diaminodichloride, cis-Platinum(II) diammine chloride, cis-Platinum(II) diamminedichloride, cis-Platinumdiamine dichloride, cis-Platinumdiammine dichloride

Description

Cisplatin is a chemotherapeutic drug that inhibits the growth of cancer cells by binding to DNA. It binds to DNA and inhibits transcription and replication, leading to the accumulation of p-glycoprotein (P-gp) inhibitor in the cell membrane, which prevents the efflux of intracellular caspase activators. This leads to an increase in apoptosis among cancer cells and a decrease in healthy tissue. The toxicology of cisplatin has been studied extensively, with low-dose groups showing no signs of toxicity.

• Brand: Biosynth

Chemical properties

• Molecular weight: 300.05 g/mol
• Formula: Cl₂H₆N₂Pt
• Purity: (Hplc) 98 To 102%
• Color/Form: Yellow Powder