Clobetasone 17-butyrate

CAS: 25122-57-0

Ref. 3D-FC20490

Product Information

• Name: Clobetasone 17-butyrate
• Synonyms: (16b)-21-Chloro-9-fluoro-16-methyl-17-(1-oxobutoxy)pregna-1,4-diene-3,11,20-trione, (16Beta)-21-Chloro-9-Fluoro-16-Methyl-3,11,20-Trioxopregna-1,4-Dien-17-Yl Butanoate, (16β)-21-Chloro-9-fluoro-16-methyl-17-(1-oxobutoxy)pregna-1,4-diene-3,11,20-trione, 21-Chloro-9-fluoro-17-hydroxy-16-beta-methylpregna-1,4-diene,3,11,20-trione butyrate, 21-Chloro-9-fluoro-17-hydroxy-16beta-methylpregna-1,4-diene-3,11,20-trione 17-butyrate, 21-Chloro-9-fluoro-17-hydroxy-16beta-methylpregna-1,4-diene-3,11,20-trione butyrate, Butyric acid, ester with 21-chloro-9-fluoro-17-hydroxy-16β-methylpregna-1,4-diene-3,11,20-trione, CCl 5537, Cci 5537, Clobetasone butyrate [USAN:JAN], Cloptison, Emovate, Eumovate, Gr 2/1214, Kindavate, Molivate, Pregna-1,4-diene-3,11,20-trione, 21-chloro-9-fluoro-16-methyl-17-(1-oxobutoxy)-, (16-beta)-, Pregna-1,4-diene-3,11,20-trione, 21-chloro-9-fluoro-16-methyl-17-(1-oxobutoxy)-, (16beta)-, Pregna-1,4-diene-3,11,20-trione, 21-chloro-9-fluoro-16-methyl-17-(1-oxobutoxy)-, (16β)-, Pregna-1,4-diene-3,11,20-trione, 21-chloro-9-fluoro-17-hydroxy-16-beta-methyl-, butyrate, Pregna-1,4-diene-3,11,20-trione, 21-chloro-9-fluoro-17-hydroxy-16β-methyl-, butyrate, Sn 203, Unii-8U0H6Xi6Eo, Clobetasone butyrate, Clobetasone butyrate

Description

Clobetasone 17-butyrate is a corticosteroid that is used for the treatment of inflammatory bowel disease. It is a prodrug that undergoes rapid and extensive metabolism in vivo to form the active metabolite clobetasol 17-propionate. The chemical stability of clobetasone 17-butyrate allows it to be stored at room temperature, which makes it an ideal candidate for use in developing countries. Clobetasone 17-butyrate has been shown to exhibit antiinflammatory activity, with statistically significant differences when compared to placebo. This drug has been shown to be effective against symptoms of bowel disease in both humans and animals. Clobetasone 17-butyrate can also be used as an analytical reagent because it binds with benzalkonium chloride and can be used for wastewater treatment.

• Brand: Biosynth

Chemical properties

• Molecular weight: 478.98 g/mol
• Formula: C₂₆H₃₂ClFO₅
• Purity: Min. 95%