Clotrimazole

CAS: 23593-75-1

Ref. 3D-FC20523

Product Information

• Name: Clotrimazole
• Synonyms: 1-[(2-Chlorophenyl)-diphenyl-methyl]-1H-imidazoleFB-5097Bay B 5097, (2-Chlorophenyl)diphenyl-1-imidazolylmethane, 1-(o-Chlorophenyldiphenylmethyl)imidazole, 1-(o-Chlorotrityl)imidazole, 1H-Imidazole, 1-[(2-chlorophenyl)diphenylmethyl]-, 1[(2-chlorophenyl)diphenylmethyl]-1H-imidazole, Agisten, Bay 5097, Bay 5907, Bay-B 5097, Canesten, Canifug, Clotrimazol, Clotrimazole ZnSO4 complex, Desamix F, Diphenyl(2-chlorophenyl)(1-imidazolyl)methane, Empecid, Femcare, Gyne-Lotrimin, Gyne-Lotrimin 7, Imidazole, 1-(o-chloro-α,α-diphenylbenzyl)-, Locasten, Lotrimin, Lotrimin AF Cream, Lotrimin AF Solution, Lotrimin Jock-Itch Cream, Lotrimin Jock-Itch Lotion, Monobaycuten, Mycelex, Mycelex 7, Mycelex G, Mycelex OTC, Mycelex Troche, Mycofug, Mycosporin, Nsc 257473, Pedisafe, Plimycol, Rimazole, Tibatin, Trimysten, Veltrim

Description

Clotrimazole is a broad-spectrum antifungal agent that inhibits the synthesis of ergosterol, a constituent of fungal cell membranes. It has been shown to be effective against Candida glabrata and other gram-positive and gram-negative bacteria, including Staphylococcus aureus. Clotrimazole also has anti-cancer properties, inhibiting the growth of certain cancer cells by interfering with DNA synthesis. It is not active against Aspergillus or Cryptococcus neoformans. Clotrimazole is used in a controlled-release preparation to maintain an optimum concentration in the skin over an extended period of time. Clotrimazole can also be used as an adjunct in the treatment of vaginal candidiasis or vulvovaginal candidiasis caused by Candida albicans. This drug binds to Dna and Rna templates, preventing their unwinding and subsequent replication. The drug also binds to pro-

• Brand: Biosynth

Chemical properties

• Molecular weight: 344.84 g/mol
• Formula: C₂₂H₁₇ClN₂
• Purity: Min. 95%
• Color/Form: White Powder