Conivaptan hydrochloride

CAS: 168626-94-6

Ref. 3D-FC20552

Product Information

• Name: Conivaptan hydrochloride
• Synonyms: N-[4-[(4,5-Dihydro-2-methylimidazo[4,5-d][1]benzazepin-6(1H)-yl)carbonyl]phenyl]-[1,1'-biphenyl]-2-carboxamide hydrochlorideVapriso lYM 087, Conivaptan Monohydrochloride, N-[4-[(4,5-dihydro-2-methylimidazo[4,5-d][1]benzazepin-6(1H)-yl)carbonyl]phenyl]-, monohydrochloride, N-{4-[(2-Methyl-4,5-dihydroimidazo[4,5-d][1]benzazepin-6(1H)-yl)carbonyl]phenyl}biphenyl-2-carboxamidhydrochlorid, N-{4-[(2-methyl-4,5-dihydroimidazo[4,5-d][1]benzazepin-6(1H)-yl)carbonyl]phenyl}biphenyl-2-carboxamide hydrochloride, N-{4-[(2-methyl-4,5-dihydroimidazo[4,5-d][1]benzazepin-6(3H)-yl)carbonyl]phenyl}biphenyl-2-carboxamide hydrochloride (1:1), N-{4-[(2-methyl-4,5-dihydroimidazo[4,5-d][1]benzazépin-6(1H)-yl)carbonyl]phenyl}biphenyl-2-carboxamide chlorhydrate, Vaprisol, Ym 087, [1,1'-biphenyl]-2-carboxamide, N-[4-[(4,5-dihydro-2-methylimidazo[4,5-d][1]benzazepin-6(1H)-yl)carbonyl]phenyl]-, monohydrochloride, [1,1′-Biphenyl]-2-carboxamide, N-[4-[(4,5-dihydro-2-methylimidazo[4,5-d][1]benzazepin-6(1H)-yl)carbonyl]phenyl]-, hydrochloride (1:1)

Description

Conivaptan hydrochloride is a selective, orally active vasopressin receptor antagonist that has been shown to be effective in the treatment of congestive heart failure. Conivaptan hydrochloride is used in experimental models to study its efficacy and safety. The long-term efficacy of conivaptan hydrochloride was demonstrated in a chronic oral study with rats. Optimum concentrations for conivaptan hydrochloride are between 0.5 and 2 mg/kg body weight, which should be administered three times daily. In patients with hepatic impairment, the concentration-time curve of conivaptan hydrochloride may be affected so that higher doses are required to achieve the desired effect. This drug also interacts with drugs such as warfarin, beta blockers, or calcium channel blockers. Patients with high body mass index or systolic pressure should not use this medication because it can lead to serious side effects.

• Brand: Biosynth

Chemical properties

• Molecular weight: 535.04 g/mol
• Formula: C₃₂H₂₇ClN₄O₂
• Purity: Min. 95%
• Color/Form: White Powder