Cotarnine iodide
CAS: 30936-27-7
Ref. 3D-FC20563
| 1mg | 152.00 € | ||
| 2mg | 227.00 € | ||
| 5mg | 427.00 € | ||
| 10mg | 570.00 € | ||
| 25mg | 905.00 € |
Product Information
- 7,8-Dihydro-4-methoxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolinium iodide
- 1,3-Dioxolo[4,5-g]isoquinolinium,7,8-dihydro-4-methoxy-6-methyl-, iodide (8CI,9CI)
- Cotarnine iodide (6CI,7CI)
- Cotarnin iodide
Cotarnine iodide is the major active alkaloid of anhalonium lewinii, a member of the order Piperales. Cotarnine iodide is a bisbenzylisoquinoline that contains an isoquinoline nucleus. It is synthesized from phenethylamines and anhalonium, which are also isoquinoline derivatives. Cotarnine iodide inhibits the synthesis of neurotransmitters such as acetylcholine in the central nervous system and has physiological effects such as sedation and muscle relaxation. It also causes closure of the pupil by blocking acetylcholinesterase activity. Cotarnine iodide binds to the nicotinic receptor sites on postganglionic neurons and blocks acetylcholinesterase activity, leading to a build-up of acetylcholine in these nerves. This can lead to paralysis of skeletal muscles by blocking transmission at neuromuscular junctions.
Chemical properties
Technical inquiry about: 3D-FC20563 Cotarnine iodide
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