Coumaphos

CAS: 56-72-4

Ref. 3D-FC20569

Product Information

• Name: Coumaphos
• Synonyms: 3-Chloro-4-methyl-7-hydroxycoumarin diethyl thiophosphoric acid ester, 3-Chloro-4-methyl-7-coumarinyl diethyl phosphorothioate, 3-Chloro-4-methylumbelliferone O-ester with O,O-diethyl phosphorothioate, 3-Chloro-7-hydroxy-4-methyl-coumarin O,O-diethyl phosphorothioate, 3-Chloro-7-hydroxy-4-methyl-coumarin O-ester with O,O-diethyl phosphorothioate, Agridip, Asuntol, Bayer 21/199, Baymix, Baymix 50, Co-ral, Co-ral (phosphate), Coumafos, Coumarin, 3-chloro-7-hydroxy-4-methyl-, O-ester with O,O-diethyl phosphorothioate, Coumphos, Cumafos, Ent 17,957, Koral, Meldane, Meldone, Muscatox, Muscotox, Nsc 8944, O,O-Diethyl 3-chloro-4-methyl-7-umbelliferone thiophosphate, O,O-Diethyl O-(3-chloro-4-methyl-2-oxo-2H-benzopyran-7-yl) phosphorothioate, O,O-Diethyl O-(3-chloro-4-methyl-7-coumarinyl) phosphorothioate, O,O-Diethyl O-3-chloro-4-methyl-2-oxo-2H-1-benzopyran-7-yl phosphorothioate, O,O-Diethyl-O-(3-chloro-4-methyl-7-coumarinyl)thiophosphate, O-(3-Chloro-4-methyl-2-oxo-2H-1-benzopyran-7-yl) O,O-diethyl phosphorothioate, O-(3-Chloro-4-methyl-2-oxo-2H-chromen-7-yl) O,O-diethyl thiophosphate, O-(3-chloro-4-methyl-2-oxo-2H-chromen-7-yl) O,O-diethyl phosphorothioate, O-3-Chloro-4-methyl-7-coumarinyl O,O-diethyl phosphorothioate, Perizin, Phosphorothioic acid O-(3-chloro-4-methyl-2-oxo-2H-1-benzopyran-7-yl) O,O-diethyl ester, Prince, Resitox, Umbelliferone, 3-chloro-4-methyl-, O,O-diethyl phosphorothioate

Description

Coumaphos is a potent insecticide that belongs to the group of antimicrobial peptides. It is used in veterinary medicine to control ticks, fleas, and other pests. Coumaphos inhibits the ryanodine receptor, which is a calcium channel in the sarcoplasmic reticulum of muscle cells. This inhibition prevents the release of calcium ions from the sarcoplasmic reticulum and consequently blocks entry into the contractile apparatus. Coumaphos has been shown to be effective against Boophilus microplus, an animal pest that causes cattle disease. The LD50 for this drug is higher than 1 g/kg when administered orally in mice or rats. When given sublethally, coumaphos does not cause significant damage to tissues or organs such as liver or kidney.br>br>Coumaphos can also inhibit acetylcholinesterase (AChE) activity in vitro and in vivo, which may have

• Brand: Biosynth

Chemical properties

• Molecular weight: 362.77 g/mol
• Formula: C₁₄H₁₆ClO₅PS
• Purity: Min. 95%
• InChI: InChI=1S/C14H16ClO5PS/c1-4-17-21(22,18-5-2)20-10-6-7-11-9(3)13(15)14(16)19-12(11)8-10/h6-8H,4-5H2,1-3H3
• InChI key: InChIKey=BXNANOICGRISHX-UHFFFAOYSA-N
• SMILES: CCOP(=S)(OCC)Oc1ccc2c(C)c(Cl)c(=O)oc2c1