O-Cresolphthalein

CAS: 596-27-0

Ref. 3D-FC30578

Product Information

• Name: O-Cresolphthalein
• Synonyms: 1(3H)-Isobenzofuranone, 3,3-bis(4-hydroxy-3-methylphenyl)-, 3,3-Bis(3-methyl-4-hydroxyphenyl)phthalide, 3,3-Bis(4-Hydroxy-M-Tolyl)Phthalide, 3,3-Bis(4-hydroxy-3-methylphenyl)-1(3H)-isobenzofuranone, 3,3-Bis(4-hydroxy-3-methylphenyl)-2-benzofuran-1-one, 3,3-bis(4-hydroxy-3-methylphenyl)-2-benzofuran-1(3H)-one, Cresolphthalein, Ortho-Cresolphthalein, Phenolphthalein, 3′,3′′-dimethyl-, o-Cresolphalein, o-Cresolphthalein

Description

O-Cresolphthalein is a gadolinium chelate that is used as a contrast agent for magnetic resonance imaging (MRI) of the brain, spine, and joints. The gadolinium ion is bound to the cresol molecule, which has an attached hydroxyl group. This complex attaches to the phosphorous pentoxide and creates a precipitate of metal hydroxides in the presence of water and sodium carbonate. O-Cresolphthalein is also used in clinical pathology to measure glomerular filtration rate (GFR), which is important for diagnosing renal disease. MRI scans are used to diagnose osteogenic genes that are associated with bone diseases such as osteoporosis.

• Brand: Biosynth

Chemical properties

• Molecular weight: 346.38 g/mol
• Formula: C₂₂H₁₈O₄
• Purity: Min. 95 Area-%
• Color/Form: Powder
• InChI: InChI=1S/C22H18O4/c1-13-11-15(7-9-19(13)23)22(16-8-10-20(24)14(2)12-16)18-6-4-3-5-17(18)21(25)26-22/h3-12,23-24H,1-2H3
• InChI key: InChIKey=CPBJMKMKNCRKQB-UHFFFAOYSA-N
• SMILES: Cc1cc(C2(c3ccc(O)c(C)c3)OC(=O)c3ccccc32)ccc1O