4-Chloro-6-methoxyquinolin-7-ol

CAS: 205448-31-3

Ref. 3D-FC30699

Product Information

• Name: 4-Chloro-6-methoxyquinolin-7-ol
• Synonyms: 7-Quinolinol, 4-chloro-6-methoxy-, 4-Chloro-7-hydroxy-6-methoxy-7-quinoline, 4-Chloro-6-methoxy-7-quinolinol

Description

4-Chloro-6-methoxyquinolin-7-ol (CMQ) is an alkali metal that inhibits the sodium/potassium ATPase pump, which is responsible for maintaining the cell's intracellular ion balance. It was discovered in a search for compounds that inhibit this enzyme and show promise in the treatment of heart diseases. CMQ has been shown to inhibit the sodium concentration in rat hearts with no effect on potassium concentrations, which may be due to its ability to bind to sodium ions but not potassium ions. The long-term effects of CMQ on human populations are unknown, as well as its effects on genotype and parameters. CMQ also has been shown to cause drug resistance mutations in bacteria, such as methicillin resistant Staphylococcus aureus (MRSA), by increasing the mutation rate. This is due to the fact that it inhibits DNA replication and protein synthesis in bacteria cells.

• Brand: Biosynth

Chemical properties

• Molecular weight: 209.63 g/mol
• Formula: C₁₀H₈ClNO₂
• Purity: Min. 95%
• Color/Form: Yellow Powder
• InChI: InChI=1S/C10H8ClNO2/c1-14-10-4-6-7(11)2-3-12-8(6)5-9(10)13/h2-5,13H,1H3
• InChI key: InChIKey=NKWZPFHSWLSOON-UHFFFAOYSA-N
• SMILES: COc1cc2c(Cl)ccnc2cc1O