Citromycetin

CAS: 478-60-4

Ref. 3D-FC32531

Product Information

• Name: Citromycetin
• Synonyms: 8,9-Dihydroxy-2-methyl-4-oxo-5H-pyrano[3,2-c]chromene-10-carboxylic acid, 4H,5H-Pyrano(3,2-c)(1)benzopyran-10-carboxylic acid, 8,9-dihydroxy-2-methyl-4-oxo-, 8,9-Dihydroxy-2-methyl-4-oxo-4H,5H-pyrano[3,2-c][1]benzopyran-10-carboxylic acid, 8,9-dihydroxy-2-methyl-4-oxo-4H,5H-pyrano[3,2-c]chromene-10-carboxylic acid, Brn 0330020, Frequentic acid, Nsc 53584, 4-19-00-03953 (Beilstein Handbook Reference)

Description

Citromycetin is a natural product that belongs to the class of diterpene antibiotics. It is an endophytic fungus that has been isolated from several plant species. Citromycetin inhibits the production of inflammatory cytokines and has been shown to have anticancer activity by inducing apoptosis in cancer cells. Citromycetin also binds to DNA and inhibits transcription, which may be due to its ability to inhibit the phosphatase PTP1B. The structure of citromycetin was elucidated using a monoclonal antibody and mass spectrometry. Citromycetin has been shown to inhibit alpha-synuclein aggregation in vitro and in vivo, which may be responsible for its anti-neurodegenerative properties.

• Brand: Biosynth

Chemical properties

• Molecular weight: 290.23 g/mol
• Formula: C₁₄H₁₀O₇
• Purity: Min. 95%
• InChI: InChI=1S/C14H10O7/c1-5-2-7(15)6-4-20-9-3-8(16)12(17)11(14(18)19)10(9)13(6)21-5/h2-3,16-17H,4H2,1H3,(H,18,19)
• InChI key: InChIKey=PKEPGKZPVDAVKI-UHFFFAOYSA-N
• SMILES: Cc1cc(=O)c2c(o1)-c1c(cc(O)c(O)c1C(=O)O)OC2