4-Chloro pyrazole
CAS: 15878-00-9
Ref. 3D-FC32604
| 25g | 144.00 € | ||
| 50g | 192.00 € | ||
| 100g | 260.00 € | ||
| 250g | 406.00 € | ||
| 500g | 544.00 € |
Product Information
- 1H-Pyrazole, 4-chloro-
- 4-Chloro-1H-Pyrazol
- 4-Chloro-1H-Pyrazole
- 4-Chloro-Pyrazol
- Akos B001464
- Art-Chem-Bb B001464
- Pyrazole, 4-chloro-
- Vitas-Bb Tbb000653
- 4-Chloropyrazole
4-Chloro pyrazole is a pyrazole derivative that has been shown to be effective as an inhibitor of aldehyde dehydrogenase. The structural formula for 4-chloro pyrazole is shown below. This compound binds to the active site of the enzyme, preventing it from catalyzing the conversion of acetaldehyde into acetic acid and thus preventing the accumulation of acetaldehyde in cells. The binding site is thought to involve a nucleophilic attack by the chlorine atom on the carbonyl group at C4 on the pyrazole ring, followed by coordination with two oxygens from water molecules. The chemical analyses indicate that 4-chloro pyrazole is not readily metabolized, which may be due to its inertness as a substrate for various enzymes or its low solubility in biological fluids.
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[[File:4-Chloro Pyrazole Structure.png|thumb|center|500px|Struct
Chemical properties
Technical inquiry about: 3D-FC32604 4-Chloro pyrazole
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