Product Information
Name:6-Chloroisatin
Synonyms:
- 6-Chloroindole-2,3-dione6-Chloro-2,3-indolinedione
Brand:Biosynth
Description:6-Chloroisatin is a potent inhibitor of bacterial growth that binds to the 50S ribosomal subunit. It has been shown to have strong inhibitory activity against tuberculosis and sulphamethoxazole-resistant strains of Mycobacterium tuberculosis. 6-Chloroisatin inhibits bacterial growth by binding to the 50S ribosomal subunit, thereby preventing protein synthesis and cell division. The electron deficient form of 6-chloroisatin reacts with the electron rich sulphamethoxazole by displacement of chloride ion from the sulphonamide ring, forming a regiospecific product that inhibits bacterial respiration. This reaction system is inhibited by activated carbon, which may be a potential therapeutic strategy for patients with drug resistant tuberculosis.
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Chemical properties
Molecular weight:181.58 g/mol
Formula:C8H4ClNO2
Purity:Min. 95%
Technical inquiry about: 6-Chloroisatin
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