6-Chloroisatin

CAS:
6341-92-0

Ref. 3D-FC32700

-Unit-kgkg

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25g

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Product Information

Name:6-Chloroisatin

Synonyms:

6-Chloroindole-2,3-dione6-Chloro-2,3-indolinedione

Brand:Biosynth

Description:

6-Chloroisatin is a potent inhibitor of bacterial growth that binds to the 50S ribosomal subunit. It has been shown to have strong inhibitory activity against tuberculosis and sulphamethoxazole-resistant strains of Mycobacterium tuberculosis. 6-Chloroisatin inhibits bacterial growth by binding to the 50S ribosomal subunit, thereby preventing protein synthesis and cell division. The electron deficient form of 6-chloroisatin reacts with the electron rich sulphamethoxazole by displacement of chloride ion from the sulphonamide ring, forming a regiospecific product that inhibits bacterial respiration. This reaction system is inhibited by activated carbon, which may be a potential therapeutic strategy for patients with drug resistant tuberculosis.

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Chemical properties

Molecular weight:181.58 g/mol

Formula:C₈H₄ClNO₂

Purity:Min. 95%

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