Cinchocaine - USP

CAS: 85-79-0

Ref. 3D-FC33247

Product Information

• Name: Cinchocaine - USP
• Synonyms: Dibucaine, 2-Butoxy-N-[2-(diethylamino)ethyl]-4-quinolinecarboxamide, 2-Butoxy-N-[2-(diethylamino)ethyl]cinchoninamide, 2-Butoxy-N-[2-(diethylamino)ethyl]quinoline-4-carboxamide, 2-butoxy-N-(2-diethylaminoethyl)quinoline-4-carboxamide, 4-Quinolinecarboxamide, 2-butoxy-N-[2-(diethylamino)ethyl]-, Cinchocain, Cinchocaine, Cinchocaine Base, Cinchoninamide, 2-butoxy-N-[2-(diethylamino)ethyl]-, Cincocainio, Dermacaine, Dibucaine (base and/or unspecified salts), Dibucaine Free Base Crystalline, Dibucaine Solution, Dibucaine Usp, Dibucaine base, N-[2-(Diethylamino)ethyl]-2-butoxycinchoninamide, Nsc 159055, Nupercainal, Nupercaine, Percamine

Description

Cinchocaine is a local anesthetic, which is used to relieve pain. Cinchocaine is a member of the amide class of local anesthetics. It has been shown to have neuronal death and mitochondrial membrane potential-inhibiting properties. Cinchocaine also binds to the hydrophobic region of voltage-sensitive potassium channels (Kv1.2), resulting in their closure and preventing action potentials from propagating through the neuron. The optimum concentration for cinchocaine is 0.1% (w/v). The optimal pH range for cinchocaine is 7.0 - 8.0, with a phase transition temperature of 78°C and a melting point of 117°C. Cinchocaine has been shown to be effective in animal models at concentrations as low as 10 µg/mL, with significant therapeutic effects observed at concentrations greater than 50 µg/mL

• Brand: Biosynth

Chemical properties

• Molecular weight: 343.46 g/mol
• Formula: C₂₀H₂₉N₃O₂
• Purity: Min. 95%
• Color/Form: White Powder
• InChI: InChI=1S/C20H29N3O2/c1-4-7-14-25-19-15-17(16-10-8-9-11-18(16)22-19)20(24)21-12-13-23(5-2)6-3/h8-11,15H,4-7,12-14H2,1-3H3,(H,21,24)
• InChI key: InChIKey=PUFQVTATUTYEAL-UHFFFAOYSA-N
• SMILES: CCCCOc1cc(C(=O)NCCN(CC)CC)c2ccccc2n1