Chelidamic acid hydrate

CAS: 138-60-3

Ref. 3D-FC34364

Product Information

• Name: Chelidamic acid hydrate
• Synonyms: 4-Oxo-1,4-dihydro-2,6-pyridinedicarboxylic acid hydrate4-Hydroxy-pyridine-2,6-dicarboxylic acid hydrate, 1,4-Dihydro-4-Oxo-2,6-Pyridinedicarboxylic Acid, 1,4-Dihydro-4-oxopyridine-2,6-dicarboxylic acid, 2,6-Pyridinedicarboxylic acid, 1,4-dihydro-4-oxo-, 2,6-Pyridinedicarboxylic acid, 1,4-dihydro-4-oxo- (8CI)(9CI), 4-Hydroxypyridine-2,6-dicarboxylic acid, 4-Oxo-1,4-Dihydropyridine-2,6-Dicarboxylate, 4-Oxo-1,4-Dihydropyridine-2,6-Dicarboxylic Acid, Chelidamic aicd, NSC 3983, Chelidamic acid

Description

Chelidamic acid hydrate is an organic compound that belongs to the group of pyridine carboxylic acids. It is a water-soluble, colorless solid with an optimum concentration in the range of 0.1 to 1.0 M. Chelidamic acid hydrate has been used as a proton carrier and was found to be a strong base with a pKb around 12.5 and a high affinity for oxygen atoms, which are present in the form of hydroxyl groups at pH 7, 8, and 9. The compound also has been observed to have cytotoxic effects on prostate cancer cells and human erythrocytes. Chelidamic acid hydrate has shown anticancer activity by causing mitochondrial membrane potential collapse in prostate cancer cells. This activity is due to hydrogen bonding interactions between the solvated electrons and the carboxylate group of the chelidamic acid hydrate molecule that are mediated by light emission from the electron transitions between

• Brand: Biosynth

Chemical properties

• Molecular weight: 183.12 g/mol
• Formula: C₇H₅NO₅•xH₂O
• Purity: Min. 95%
• Color/Form: White Powder