8-chloroquinoline

Ref. 3D-FC35037

Product Information

• Name: 8-chloroquinoline
• Brand: Biosynth
• Description: 8-Chloroquinoline is an organochlorine compound that has anti-malarial, anti-parasitic, and anti-bacterial properties. It binds to the parasite's enzyme hemozoin synthase to inhibit the production of hemozoin. 8-Chloroquinoline also inhibits bacterial growth by binding to the enzyme DNA gyrase and prevents bacterial replication. The binding of 8-chloroquinoline to DNA gyrase inactivates it, thus preventing supercoiling of the bacterial DNA. This causes a structural change in the DNA helix that inhibits transcription and replication. 8-Chloroquinoline has been shown to be effective against Mycobacterium tuberculosis with minimal toxicity for liver cells.

Chemical properties

• Molecular weight: 163.6 g/mol
• Formula: C₉H₆ClN
• Purity: Min. 95%