1-(3-Chloropropyl)-1,3-dihydro-2H-benzimidazole-2-one

CAS: 62780-89-6

Ref. 3D-FC36775

Product Information

• Name: 1-(3-Chloropropyl)-1,3-dihydro-2H-benzimidazole-2-one
• Brand: Biosynth

Description

Phenylmethyl (PM) is a drug that belongs to the class of phenylmethanesulfonamides. It is used in the treatment of diarrhea, specifically in cases where there are no other suitable anti-diarrheal drugs available. The active form of PM is 1-(3-chloropropyl)-1,3-dihydro-2H-benzimidazole-2-one (PCP). This drug inhibits bacterial growth by binding to the 50S ribosomal subunit and inhibiting protein synthesis. PCP has been shown to have a narrow spectrum of activity against most enteric bacteria and some protozoa. The drug is poorly absorbed from the gastrointestinal tract and does not cross the blood–brain barrier, which limits its use for systemic infections.

Chemical properties

• Molecular weight: 210.66 g/mol
• Formula: C₁₀H₁₁ClN₂O
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C10H11ClN2O/c11-6-3-7-13-9-5-2-1-4-8(9)12-10(13)14/h1-2,4-5H,3,6-7H2,(H,12,14)
• InChI key: InChIKey=GUMPYDGUYXOYML-UHFFFAOYSA-N
• SMILES: O=c1[nH]c2ccccc2n1CCCCl