7-Chloroquinaldine

CAS: 4965-33-7

Ref. 3D-FC40565

Product Information

• Name: 7-Chloroquinaldine
• Synonyms: 7-Chloro-2-methyl-quinoline, 7-Chloro-2-methylquinoline, Chloroquinaldine, Quinaldine, 7-chloro-, Quinoline, 7-chloro-2-methyl-
• CAS: 4965-33-7

Description

7-Chloroquinaldine is a redox potential that is used in the industrial production of quinoline. It is also used as an intermediate for the synthesis of other organic compounds, such as 7-chloroquinoline and chloroquine. The reaction generally starts with sodium hydroxide solution (NaOH) and pyridine (C5H5N), which react to form sodium pyridinium chloride (NaC5H4N+Cl−). This compound reacts with chloroform (CHCl3) to form 7-chloroquinoline and hydrochloric acid (HCl). The reaction product can be purified by crystallization or by washing with water. A Friedel-Crafts reaction is then conducted using aluminum chloride, which reacts with the 7-chloroquinolone to produce 3,4-dichloropyridine. Finally, this compound reacts with hydrogen peroxide and potassium hydroxide to produce hydrogen chloride

• Brand: Biosynth

Chemical properties

• Molecular weight: 177.63 g/mol
• Formula: C₁₀H₈ClN
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C10H8ClN/c1-7-2-3-8-4-5-9(11)6-10(8)12-7/h2-6H,1H3
• InChI key: InChIKey=WQZQFYRSYLXBGP-UHFFFAOYSA-N
• SMILES: Cc1ccc2ccc(Cl)cc2n1