5-Chloro-7-iodo-8-hydroxyquinoline

CAS: 130-26-7

Ref. 3D-FC40594

Product Information

• Name: 5-Chloro-7-iodo-8-hydroxyquinoline
• Synonyms: Clioquinol5-Chloro-7-iodoquinolin-8-ol5-Chloro-7-iodo-8-hydroxyquinoline, 5-Chloro-7-iodo-8-oxyquinoline, 5-Chloro-7-iodo-8-quinolinol, 5-Chloro-7-iodoquinolin-8-ol, 7-Iodo-5-chloro-8-hydroxyquinoline, 7-Iodo-5-chloroxine, 8-Hydroxy-7-iodo-5-chloroquinoline, 8-Quinolinol, 5-chloro-7-iodo-, Alchloquin, Amebil, Amoenol, Bactol, Barquinol, Budoform, Chinoform, Chloroiodoquin, Chloroiodoquine, Chlorojodochin, Cifoform, Clioquinol, Cliquinol, Cort-Quin, Dioquinol, Dizenterol, Eczecidin, Emaform, Entero-Vioform, Enteroquinol, Enteroseptol, Enterozol, Entrokin, Hi-Eneterol, Hi-Enterol, Iodenterol, Iodochlorhydroxyquin, Iodochlorhydroxyquinol, Iodochlorohydroxyquin, Iodochlorohydroxyquinoline, Iodochloroquine, Iodochloroxine, Iodochloroxyquinoline, Iodoenterol, Iodoxyquinoline, Lekosept, NSC 3531, NSC 74938, Nioform, Quin-O-Creme, Quinambicide, Quinidochlor, Quiniodochlor, Quinoform, Quinoform (antiseptic), Rheaform, Rheaform Boluses, Rometin, Vioform, Vioformio

Description

5-Chloro-7-iodo-8-hydroxyquinoline is a metal chelate that has been shown to have pharmacological effects in experimental animals. It has antioxidative properties and can protect against oxidative injury. 5-Chloro-7-iodo-8-hydroxyquinoline was found to be toxic in various animal models, including the neuronal death and mitochondrial membrane potential. This toxicity may be due to its ability to inhibit the activity of DNA polymerase and protein synthesis. The compound also showed significant cytotoxicity at low concentrations, but had no significant cytotoxicity at higher concentrations. 5-Chloro-7-iodo-8-hydroxyquinoline is similar in structure to clioquinol, which has been shown to have neurotoxic effects in humans.

• Brand: Biosynth

Chemical properties

• Molecular weight: 305.5 g/mol
• Formula: C₉H₅ClINO
• Purity: Min. 95 Area-%
• Color/Form: Powder