7-Chloro-4-hydroxyquinoline
CAS: 86-99-7
Ref. 3D-FC40597
| 5g | 143.00 € | ||
| 10g | 199.00 € | ||
| 25g | 357.00 € | ||
| 50g | 489.00 € | ||
| 100g | 635.00 € |
Product Information
- 4-Hydroxy-7-chloroquinoline
- 4-Quinolinol, 7-chloro-
- 7-Chloro-4-Quinolinol
- 7-chloroquinolin-4(1H)-one
- NSC 38928
7-Chloro-4-hydroxyquinoline is a quinoline derivative that has been shown to be an effective anti-tuberculosis agent. It inhibits bacterial growth by binding to DNA and RNA, preventing transcription and replication. The high frequency of human activity has been shown using a patch-clamp technique on human erythrocytes. This active form is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. 7-Chloro-4-hydroxyquinoline also specifically binds to markers expressed at high levels in Mycobacterium tuberculosis strains (e.g., ESX-1 secretion system protein) and inhibits cell growth in culture.
Chemical properties
Technical inquiry about: 3D-FC40597 7-Chloro-4-hydroxyquinoline
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