Cyclo(Gly-L-Gln)

CAS: 52662-00-7

Ref. 3D-FC49426

Product Information

• Name: Cyclo(Gly-L-Gln)
• Synonyms: Cyclo(-Gly-Gln)(2S)-Hexahydro-3,6-dioxo-pyrazinepropanamide

Description

Cyclo(Gly-L-Gln) is an endogenous compound related to the cyclic peptide family, which includes neuropeptides such as β-endorphin. Cyclo(Gly-L-Gln) has been found to increase intracerebroventricular (i.c.v.) levels of β-endorphin and dopamine in rats, leading to a depression recovery response. The molecule has dose-dependent effects on the opioid receptor, with low doses acting as an agonist and high doses acting as an antagonist. This drug is also not polar and has a conformation that is similar to nicotine, which may explain its addictive properties and ability to induce dependence.

• Brand: Biosynth

Chemical properties

• Molecular weight: 185.18 g/mol
• Formula: C₇H₁₁N₃O₃
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C7H11N3O3/c8-5(11)2-1-4-7(13)9-3-6(12)10-4/h4H,1-3H2,(H2,8,11)(H,9,13)(H,10,12)/t4-/m0/s1
• InChI key: InChIKey=PWADXPITHGKDSY-BYPYZUCNSA-N
• SMILES: NC(=O)CC[C@@H]1NC(=O)CNC1=O