Cyclo(-Phe-Pro)

CAS: 3705-26-8

Ref. 3D-FC49481

Product Information

• Name: Cyclo(-Phe-Pro)
• Synonyms: Cyclo-L-phenylalanyl-L-proline, (3S,8aS)-3-benzylhexahydropyrrolo[1,2-a]pyrazine-1,4-dione, (3S,8aS)-Hexahydro-3-(phenylmethyl)pyrrolo[1,2-a]pyrazine-1,4-dione, 3-Benzylhexahydropyrrolo[1,2-A]Pyrazine-1,4-Dione, <span class="text-smallcaps">L</smallcap>-Phenylalanyl-<smallcap>L</span>-proline lactam, <span class="text-smallcaps">L</smallcap>-Prolyl-<smallcap>L</span>-phenylalanine diketopiperazine, Cyclo(<span class="text-smallcaps">L</smallcap>-Phe-<smallcap>L</span>-Pro), Cyclo(<span class="text-smallcaps">L</smallcap>-Pro-<smallcap>L</span>-Phe), Cyclo(<span class="text-smallcaps">L</smallcap>-phenylalanyl-<smallcap>L</span>-prolyl-), Cyclo(<span class="text-smallcaps">L</smallcap>-prolyl-<smallcap>L</span>-phenylalanyl), Maculosin 2, Maculosine 2, Pyrrolo[1,2-a]pyrazine-1,4-dione, 3-benzylhexahydro-, (3S,8aS)-, Pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro-3-(phenylmethyl)-, (3S,8aS)-, Pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro-3-(phenylmethyl)-, (3S-trans)-, Smfei 02

Description

Cyclo-Phe-Pro is an intermolecular hydrogen bond that has been shown to inhibit the growth of viruses. Cyclo-Phe-Pro binds to the hydrophobic region on viral capsid proteins and inhibits their uptake into cells, which may be due to its ability to form hydrogen bonds with the amino acid serine in these proteins. It also has antimicrobial activity against a number of bacterial species and can be used as a pre-preparation for high performance liquid chromatography (HPLC).

• Brand: Biosynth

Chemical properties

• Molecular weight: 244.29 g/mol
• Formula: C₁₄H₁₆N₂O₂
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C14H16N2O2/c17-13-12-7-4-8-16(12)14(18)11(15-13)9-10-5-2-1-3-6-10/h1-3,5-6,11-12H,4,7-9H2,(H,15,17)/t11-,12-/m0/s1
• InChI key: InChIKey=QZBUWPVZSXDWSB-RYUDHWBXSA-N
• SMILES: O=C1N[C@@H](Cc2ccccc2)C(=O)N2CCC[C@@H]12