2-Chloro-3-(hydroxymethyl)pyridine

CAS: 42330-59-6

Ref. 3D-FC50835

Product Information

• Name: 2-Chloro-3-(hydroxymethyl)pyridine
• Synonyms: (2-Chloro-3-pyridinyl)methanol, (2-Chloropyridin-3-Yl)Methanol, 2-Chloro-3-hydroxymethylpyridine, 2-Chloro-3-pyridinemethanol, 2-Chloro-3-pyridylmethanol, 2-Choro-3-(hydroxymethyl)pyridine, 3-Pyridinemethanol, 2-chloro-, 2-Chloro-3-Pyridinyl Methanol

Description

2-Chloro-3-(hydroxymethyl)pyridine is an organic compound that is used as a building block for the synthesis of other heterocycles. This compound can be synthesized from 2-chloronicotinic acid, which is obtained by oxidation of nicotine with sodium hypochlorite in the presence of potassium ion. The reaction proceeds via a cleavage of the C-Cl bond and formation of a pyridine ring. The catalytic process can be performed at room temperature and at atmospheric pressure in a variety of solvents, including water.
2-Chloro-3-(hydroxymethyl)pyridine has been shown to have high yields for the preparation of compounds such as 2,4-dichloropyridine and 4,5-dichloropyrimidine. It also has been used in the preparation of pharmaceuticals such as atrial natriuretic factor (ANF).

• Brand: Biosynth

Chemical properties

• Molecular weight: 143.57 g/mol
• Formula: C₆H₆ClNO
• Purity: Min. 98 Area-%
• Color/Form: Powder
• InChI: InChI=1S/C6H6ClNO/c7-6-5(4-9)2-1-3-8-6/h1-3,9H,4H2
• InChI key: InChIKey=HMPDWSBKPCOQDW-UHFFFAOYSA-N
• SMILES: OCc1cccnc1Cl