4-Chloro-2-phenylquinazoline

CAS: 6484-25-9

Ref. 3D-FC50857

Product Information

• Name: 4-Chloro-2-phenylquinazoline
• Brand: Biosynth
• Description: 4-Chloro-2-phenylquinazoline is a ligand that inhibits the growth of bacteria by binding to their DNA. It has a molecular weight of 242.6 g/mol, and can be synthesized in two steps from 2-phenylaniline and o-chloroacetophenone. The pharmacokinetic properties of this compound have been studied using magnetic nanoparticles. 4-Chloro-2-phenylquinazoline has been shown to inhibit cancer cells and also has anti-inflammatory properties, which may be due to its ability to inhibit prostaglandin synthesis. This ligand binds to the nitrogen nucleophiles on the bacterial cell wall (e.g., trichophyton mentagrophytes) and prevents them from reacting with chlorine atoms in the environment, thus inhibiting bacterial growth.

Chemical properties

• Molecular weight: 240.69 g/mol
• Formula: C₁₄H₉ClN₂
• Purity: Min. 95%
• Color/Form: White Powder
• InChI: InChI=1S/C14H9ClN2/c15-13-11-8-4-5-9-12(11)16-14(17-13)10-6-2-1-3-7-10/h1-9H
• InChI key: InChIKey=OBHKONRNYCDRKM-UHFFFAOYSA-N
• SMILES: Clc1nc(-c2ccccc2)nc2ccccc12