Corydaline

CAS: 518-69-4

Ref. 3D-FC52358

Product Information

• Name: Corydaline
• Synonyms: (13S,13AR)-2,3,9,10-tetramethoxy-13-methyl-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinoline, (13S,13aR)-2,3,9,10-tetramethoxy-13-methyl-5,8,13,13a-tetrahydro-6H-isoquino[3,2-a]isoquinoline, (13S,13aR)-5,8,13,13a-Tetrahydro-2,3,9,10-tetramethoxy-13-methyl-6H-dibenzo[a,g]quinolizine, 13a-beta-Berbine, 2,3,9,10-tetramethoxy-13-alpha-methyl- (8CI), 13abeta-Berbine, 2,3,9,10-tetramethoxy-13alpha-methyl- (8CI), 13aβ-Berbine, 2,3,9,10-tetramethoxy-13α-methyl-, 2,3,9,10-tetramethoxy-13-methyl-5,8,13,13a-tetrahydro-6H-isoquino[3,2-a]isoquinoline, 6H-Dibenzo(a,g)quinolizine, 5,8,13,13a-tetrahydro-2,3,9,10-tetramethoxy-13-methyl-, (13S-E)-, 6H-Dibenzo(a,g)quinolizine, 5,8,13,13a-tetrahydro-2,3,9,10-tetramethoxy-13-methyl-, (13S-trans)- (9CI), 6H-Dibenzo[a,g]quinolizine, 5,8,13,13a-tetrahydro-2,3,9,10-tetramethoxy-13-methyl-, (13S,13aR)-, 6H-Dibenzo[a,g]quinolizine, 5,8,13,13a-tetrahydro-2,3,9,10-tetramethoxy-13-methyl-, (13S-trans)-, 7,8,13,13α-Tetrahydrocorydaline, Berbine, 2,3,9,10-tetramethoxy-13-methyl-, Brn 0096972, Corydalin, Nsc 406036, d-Corydaline

Description

Corydaline is a natural compound that belongs to the class of alkaloids. It has been found to have a matrix effect on enzymes, including benzalkonium chloride and protopine, as well as inhibitory properties against receptor activity. Corydaline has been shown to have an anti-inflammatory effect in vitro by inhibiting prostaglandin synthesis and suppressing the production of inflammatory cytokines. This drug also has a protective effect against oxidative damage induced by benzalkonium chloride and inhibits the growth of bacteria such as Staphylococcus aureus. The concentration-time curve for corydaline shows a short half-life with high absorption and distribution rates. The pharmacokinetics of corydaline are affected by co2 flow rate and human serum albumin levels.

• Brand: Biosynth

Chemical properties

• Molecular weight: 369.45 g/mol
• Formula: C₂₂H₂₇NO₄
• Purity: Min. 98%
• Color/Form: White Off-White Powder
• InChI: InChI=1S/C22H27NO4/c1-13-15-6-7-18(24-2)22(27-5)17(15)12-23-9-8-14-10-19(25-3)20(26-4)11-16(14)21(13)23/h6-7,10-11,13,21H,8-9,12H2,1-5H3/t13-,21+/m0/s1
• InChI key: InChIKey=VRSRXLJTYQVOHC-YEJXKQKISA-N
• SMILES: COc1cc2c(cc1OC)[C@H]1[C@@H](C)c3ccc(OC)c(OC)c3CN1CC2