5-Chloroisatin

CAS: 17630-76-1

Ref. 3D-FC52486

Product Information

• Name: 5-Chloroisatin
• Synonyms: 5-Chlor-2,3-dioxoindolin5-Chloro-1H-indole-2,3-dione, 1H-Indole-2,3-dione, 5-chloro-, 5-Chlor-2,3-Dioxoindolin, 5-Chlor-2,3-Indolindion, 5-Chlorisatide, 5-Chloro-1H-Indole-2,3-Dione, 5-Chloro-2,3-Indolinedione, 5-Chloro-2,3-indoledione, 5-Chloroindole-2,3-Dione, Akos Bbs-00000996, Indole-2,3-dione, 5-chloro-, Isatin, 5-chloro-, NSC 135811, Timtec-Bb Sbb003741

Description

5-Chloroisatin is a natural compound that is structurally similar to the potent anticancer agent 5-fluorouracil. 5-Chloroisatin has been shown to inhibit the growth of human breast cancer cells (MDA-MB-231) in vitro and in vivo. 5-chloroisatin forms stable complexes with malonic acid and hydrochloric acid, which are necessary for the reaction mechanism. The chemical structures of 5-chloroisatin, its reaction mechanism, and inhibition properties have been elucidated using FTIR spectroscopy, electrochemical impedance spectroscopy, and cell culture experiments. This compound also inhibits epidermal growth factor receptor (EGFR) signaling pathways by binding to EGFR inhibitor molecules that are expressed on the surface of cancer cells.

• Brand: Biosynth

Chemical properties

• Molecular weight: 181.58 g/mol
• Formula: C₈H₄ClNO₂
• Color/Form: Powder