Cyclopropanesulfonyl chloride

CAS: 139631-62-2

Ref. 3D-FC52987

Product Information

• Name: Cyclopropanesulfonyl chloride
• Synonyms: Chlorocyclopropylsulfone Cyclopropylsulfonyl chloride
• Brand: Biosynth

Description

Cyclopropanesulfonyl chloride (CPSC) is a bicyclic heterocycle that has been shown to have potent inhibitory activity against the human pathogens hepatitis B virus, dengue virus, and influenza A virus. CPSC inhibits the NS3 protease of these viruses by forming hydrogen bonding interactions with the nucleophilic nitrogen atom of the enzyme and also by competing with a chloride ion for binding to the chlorine atom on the enzyme. It also inhibits HIV-1 infection in cell culture experiments. CPSC has been found to be effective in preventing inflammation caused by cytokines, such as interleukin-1β, tumor necrosis factor-α, and prostaglandin E2. The inhibition of inflammatory cytokines may be due to its ability to bind glucocorticoid receptors.

Chemical properties

• Molecular weight: 140.59 g/mol
• Formula: C₃H₅ClO₂S
• Purity: Min. 99.0%
• Color/Form: Clear Liquid
• InChI: InChI=1S/C3H5ClO2S/c4-7(5,6)3-1-2-3/h3H,1-2H2
• InChI key: InChIKey=PFWWSGFPICCWGU-UHFFFAOYSA-N
• SMILES: O=S(=O)(Cl)C1CC1