4-Chloro-3-nitroacetophenone
CAS: 5465-65-6
Ref. 3D-FC54339
| 1kg | Discontinued | ||
| 25g | Discontinued | ||
| 50g | Discontinued | ||
| 100g | Discontinued | ||
| 250g | Discontinued | ||
| 500g | Discontinued |
Product Information
- 1-(4-Chloro-3-nitrophenyl)ethanone
- 1-(4-Chloro-2-Nitro-Phenyl)Ethanone
- 1-(4-Chloro-3-Nitrophenyl)Ethanone
- 1-Acetyl-4-chloro-3-nitrobenzene
- 2-Chloro-5-acetylnitrobenzene
- 3'-Nitro-4'-Chlorocetophenone
- 3′-Nitro-4′-chloroacetophenone
- 4-Acetyl-1-chloro-2-nitrobenzene
- Acetophenone, 4′-chloro-3′-nitro-
- Ethanone, 1-(4-chloro-3-nitrophenyl)-
- See more synonyms
- NSC 25820
- 4′-Chloro-3′-nitroacetophenone
- 4'-Chloro-3'-nitroacetophenone
4-Chloro-3-nitroacetophenone is a phenothiazine drug that is used in the treatment of lung conditions. It binds to the active site of human cytochrome P450, which is an enzyme that metabolizes many drugs and other foreign substances. 4-Chloro-3-nitroacetophenone inhibits the reaction by binding to the chloride ion and preventing it from leaving the enzyme's active site, which is necessary for its function. The drug has been shown to have a high affinity for protozoan tetrahymena, an organism that has been widely used as a model system in biochemistry research. 4-Chloro-3-nitroacetophenone also inhibits biochemical reactions involving nucleophilic substrates such as quinoline derivatives. The reaction rate of these substrates is decreased by this drug due to its ability to compete with water molecules for the nucleophilic reaction intermediate.
