alpha-Cyano-3-hydroxycinnamic acid

CAS: 54673-07-3

Ref. 3D-FC54852

Product Information

• Name: alpha-Cyano-3-hydroxycinnamic acid
• Synonyms: 2-Cyano-3-(3-hydroxyphenyl)acrylic acid, (2E)-2-cyano-3-(3-hydroxyphenyl)prop-2-enoate, (2E)-2-cyano-3-(3-hydroxyphenyl)prop-2-enoic acid, (2Z)-3-cyano-3-(3-hydroxyphenyl)prop-2-enoic acid, 2-Cyano-3-(3-hydroxyphenyl)-2-propenoic acid, 2-Propenoic acid, 2-cyano-3-(3-hydroxyphenyl)-, Cinnamic acid, α-cyano-m-hydroxy-, Ethyl α-cyano-3′-hydroxycinnamate, alpha-Cyano-3-hydroxycinnamate, alpha-Cyano-m-hydroxycinnamic acid, α-Cyano-3-hydroxycinnamic acid, α-Cyano-m-hydroxycinnamic acid

Description

alpha-Cyano-3-hydroxycinnamic acid is a mitochondrial matrix analog that has been shown to inhibit the uptake of carnitine, glutamate, and branched-chain amino acids. This compound also inhibits the activity of glyceraldehyde-3-phosphate dehydrogenase and dodecyl CoA dehydrogenase, which are enzymes involved in the production of cellular energy. alpha-Cyano-3-hydroxycinnamic acid also inhibits the synthesis of mitochondrial DNA and RNA. The compound binds to the enzyme succinate dehydrogenase, inhibiting its function. This inhibition leads to a decrease in cellular energy production and an increase in oxidative stress.

• Brand: Biosynth

Chemical properties

• Molecular weight: 189.17 g/mol
• Formula: C₁₀H₇NO₃
• Purity: Min. 95%
• Color/Form: Powder