2-Chloro-4-methoxybenzoic acid

CAS: 21971-21-1

Ref. 3D-FC55199

Product Information

• Name: 2-Chloro-4-methoxybenzoic acid
• Synonyms: Benzoic acid, 2-chloro-4-methoxy-, 2-Chloro-4-methoxy-benzoic acid；

Description

2-Chloro-4-methoxybenzoic acid is a model compound for the screening of acridones, which are a class of compounds with anticancer activity. 2-Chloro-4-methoxybenzoic acid has been shown to inhibit potassium t-butoxide efflux in cancer cells and induce multidrug resistance in cancer cells. Furthermore, it has been shown that 2-Chloro-4-methoxybenzoic acid inhibits mitoxantrone efflux in cancer cells, leading to an increase in mitoxantrone cytotoxicity. This compound is also able to induce a phenotype change from cancerous to normal and can be used as a chemotherapeutic agent against cancers.

• Brand: Biosynth

Chemical properties

• Molecular weight: 186.59 g/mol
• Formula: C₈H₇ClO₃
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C8H7ClO3/c1-12-5-2-3-6(8(10)11)7(9)4-5/h2-4H,1H3,(H,10,11)
• InChI key: InChIKey=IBANGHTVBPZCHF-UHFFFAOYSA-N
• SMILES: COc1ccc(C(=O)O)c(Cl)c1