2-Chloro-5-methoxybenzoic acid

CAS: 6280-89-3

Ref. 3D-FC55353

Product Information

• Name: 2-Chloro-5-methoxybenzoic acid
• Synonyms: 6-Chloro-3-methoxybenzoic acid, 6-Chloro-m-anisic acid, Benzoic acid, 2-chloro-5-methoxy-, NSC 6159, m-Anisic acid, 6-chloro-

Description

2-Chloro-5-methoxybenzoic acid (2CMB) is a copper chelator that has been shown to have antagonistic properties against microglia cells. 2CMB is synthesized from 2,5-dichlorobenzoic acid and methoxylamine. It has been shown to inhibit the synthesis of inflammatory mediators in rat spinal cord microglia cells by inhibiting the activity of polyphosphoric acid, anions and additives. 2CMB also has a high affinity for chloride ions and can be used as a tracer to measure chloride profiles. 2CMB reacts with copper ions at a slow rate and can be used as an indicator for the presence of microglia cells.

• Brand: Biosynth

Chemical properties

• Molecular weight: 186.59 g/mol
• Formula: C₈H₇ClO₃
• Purity: Min. 95%
• InChI: InChI=1S/C8H7ClO3/c1-12-5-2-3-7(9)6(4-5)8(10)11/h2-4H,1H3,(H,10,11)
• InChI key: InChIKey=AQHFCRYZABKUEV-UHFFFAOYSA-N
• SMILES: COc1ccc(Cl)c(C(=O)O)c1