2-chloro-n-(4-chlorophenyl)acetamide

CAS: 3289-75-6

Ref. 3D-FC59259

Product Information

• Name: 2-chloro-n-(4-chlorophenyl)acetamide
• Synonyms: Acetamide, 2-chloro-N-(4-chlorophenyl)-, Ai3-23540, Nsc 8369, 2-chloro-N-(4-chlorophenyl)acetamide

Description

2-Chloro-N-(4-chlorophenyl)acetamide (2CPA) is an antimycobacterial agent that inhibits the growth of Mycobacterium tuberculosis. The antimycobacterial activity of 2CPA has been demonstrated in a dilution method, where it reduced the number of viable cells in cultures of M. tuberculosis and Mycobacterium smegmatis. The antimicrobial activity of 2CPA was confirmed using a fluorescence assay, which showed that this compound is active against M. tuberculosis H37Rv and M. smegmatis at concentrations above 0.1 mM. 2CPA also has a potent bactericidal effect on Staphylococcus aureus with an MIC value of 0.06 mg/mL at 30 minutes and is active against Enterococcus faecalis with an MIC value of 4 mg/mL at 30 minutes.

• Brand: Biosynth

Chemical properties

• Molecular weight: 204.05 g/mol
• Formula: C₈H₇Cl₂NO
• Purity: Min. 95%
• InChI: InChI=1S/C8H7Cl2NO/c9-5-8(12)11-7-3-1-6(10)2-4-7/h1-4H,5H2,(H,11,12)
• InChI key: InChIKey=UDRCRMHFHHTVSN-UHFFFAOYSA-N
• SMILES: O=C(CCl)Nc1ccc(Cl)cc1