4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)phenoxy]pyridine-2-carboxylic acid

Ref. 3D-FC59377

Product Information

• Name: 4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)phenoxy]pyridine-2-carboxylic acid
• Brand: Biosynth
• Description: Regorafenib is a multikinase inhibitor that belongs to the group of targeted therapies. It has been shown to be effective in the treatment of advanced hepatocellular carcinoma and pancreatic cancer. Regorafenib inhibits all three cytochrome P450s (CYP1A2, CYP2C8, and CYP3A4) and can also inhibit other drug metabolizing enzymes such as UGT1A1. Regorafenib is not active against bacteria or fungi, but it has been shown to have anti-inflammatory properties in vitro.

Chemical properties

• Molecular weight: 451.78 g/mol
• Formula: C₂₀H₁₃N₃O₄F₃Cl
• Purity: Min. 95%