Product Information
Name:Carmofur
Synonyms:
- 5-Fluoro-1-hexylcarbamoyluracil
Brand:Biosynth
Description:Carmofur is a fluorouracil derivative that interferes with nucleotide metabolism and consequently with synthesis of RNA and DNA, leading to cytotoxic and antineoplastic effects. Carmofur inhibits also other enzymes such as lysosomal acid ceramidase and the main protease from coronaviruses. For the SARS-CoV-2 main protease Mpro, carmofur was characterised as a covalent inhibitor with IC50 of 1.82 μM and EC50 of 24.30 μM.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:257.26 g/mol
Formula:C11H16FN3O3
Purity:Min. 95%
Color/Form:White Powder
InChI:InChI=1S/C11H16FN3O3/c1-2-3-4-5-6-13-10(17)15-7-8(12)9(16)14-11(15)18/h7H,2-6H2,1H3,(H,13,17)(H,14,16,18)
InChI key:InChIKey=AOCCBINRVIKJHY-UHFFFAOYSA-N
SMILES:CCCCCCNC(=O)n1cc(F)c(=O)[nH]c1=O
Technical inquiry about: Carmofur
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