3-Chlorobenzhydrazide

CAS: 1673-47-8

Ref. 3D-FC61152

Product Information

• Name: 3-Chlorobenzhydrazide
• Synonyms: (3-Chlorobenzoyl)hydrazine, (m-Chlorobenzoyl)hydrazine, 3-Chlorobenzene-1-Carbohydrazide, 3-Chlorobenzenecarboxylic acid hydrazide, 3-Chlorobenzhydrazide, (3-Chlorobenzoic acid hydrazide), 3-Chlorobenzohydrazide, 3-Chlorobenzohydroazide, 3-Chlorobenzoic Acid Hydrazide, 3-Chlorobenzoic Hydrazide, 3-Chlorobenzoyl hydrazide, Akos Bbs-00004508, Asischem D51116, Benzoic acid, 3-chloro-, hydrazide, Benzoic acid, m-chloro-, hydrazide, Specs An-068/40169986, m-Chlorobenzoic acid hydrazide, m-Chlorobenzoic hydrazide, m-Chlorobenzoyl hydrazide

Description

3-Chlorobenzhydrazide is a dihedral molecule that can be classified as an antibacterial and antimycobacterial agent. It has the capability to inhibit bacterial growth by binding to the active site of their ribosomal 50S subunit, thereby inhibiting protein synthesis. 3-Chlorobenzhydrazide also inhibits sodium channels in myocytes, which may lead to heart problems. 3-Chlorobenzhydrazide is also known for its inotropic effects on the heart muscle and its ability to stimulate hormones such as adrenaline and noradrenaline. The crystal x-ray diffraction study revealed that 3-chlorobenzhydrazide forms a hydrogen bond with hydroxyl groups of amino acids in proteins. This property makes it an effective antibacterial agent against Gram-positive bacteria such as staphylococci and Mycobacteria tuberculosis.

• Brand: Biosynth

Chemical properties

• Molecular weight: 170.6 g/mol
• Formula: C₇H₇ClN₂O
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C7H7ClN2O/c8-6-3-1-2-5(4-6)7(11)10-9/h1-4H,9H2,(H,10,11)
• InChI key: InChIKey=PHRDZSRVSVNQRN-UHFFFAOYSA-N
• SMILES: NNC(=O)c1cccc(Cl)c1